RESEARCH: LIQUID-PHASE-SEPARATION
FOLDING PROJECT #16566 PROFILE

This project simulates how liquids separate into different layers when you add special peptides (ADMA, ARG, LYS) and RNA. They explore how these mixtures change at different concentrations.

16550: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16551, 16560, 16568: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16552, 16561, 16567: Liquid-liquid Phase separation simulation for condensate and added peptide ARG 16553, 16562, 16569: Liquid-liquid Phase separation simulation for condensate and added peptide LYS 16554: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA 16555, 16576: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA 16556: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA 16557, 16563, 16572: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA, concentration 3.7 mM 16558, 16564, 16566, 16571: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA, concentration 3.7 mM 16559, 16565, 16573: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA, concentration 3.7 mM 16570.

Liquid-liquid Phase separation

The process of two immiscible liquids separating into distinct phases.

Liquid-liquid phase separation is a phenomenon where two liquids that don't mix, like oil and water, form separate layers. In biology, this happens when certain molecules in cells clump together and create distinct compartments. This is important for processes like gene regulation and protein synthesis.

Condensate

A concentrated solution or mixture of substances.

In biology, a condensate refers to a dense, gel-like structure formed by the aggregation of molecules within a cell. These condensates can act as compartments for specific biological processes.

Peptide

A short chain of amino acids.

Peptides are small chains of amino acids linked together. They are important for many biological processes, including signaling and regulating enzyme activity.

ADMA

Arginine Dimethylarginine

ADMA is a molecule that can modify arginine, an amino acid important for blood vessel function. High levels of ADMA are associated with cardiovascular disease.

ARG

Arginine

Arginine is an amino acid that plays a crucial role in protein synthesis and various biological processes. It's involved in nitric oxide production, which helps regulate blood pressure.

LYS

Lysine

Lysine is an essential amino acid that our bodies need to function properly. It's involved in protein synthesis, enzyme activity, and the production of hormones.

RNA

Ribonucleic Acid

RNA is a molecule that plays a crucial role in protein synthesis. It carries genetic information from DNA to ribosomes, where proteins are made.