RESEARCH: LIQUID-PHASE-SEPARATION
FOLDING PROJECT #16560 PROFILE

This project simulates how liquids separate into droplets (like oil and water). Scientists are looking at how adding different molecules, like peptides and RNA, changes this separation. They're studying how these molecules might clump together in cells to form important structures.

16550: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16551, 16560, 16568: Liquid-liquid Phase separation simulation for condensate and added peptide ADMA 16552, 16561, 16567: Liquid-liquid Phase separation simulation for condensate and added peptide ARG 16553, 16562, 16569: Liquid-liquid Phase separation simulation for condensate and added peptide LYS 16554: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA 16555, 16577: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA 16556: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA 16557, 16563, 16575: Liquid-liquid Phase separation simulation for condensate containing peptide ADMA and RNA, concentration 3.7 mM 16558, 16564, 16566, 16574: Liquid-liquid Phase separation simulation for condensate containing peptide ARG and RNA, concentration 3.7 mM 16559, 16565, 16576: Liquid-liquid Phase separation simulation for condensate containing peptide LYS and RNA, concentration 3.7 mM 16570: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM 16571: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide ADMA 16572: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide ARG 16573: Liquid-liquid Phase separation simulation for condensate containing 16 peptide ARG and 16 RNA molecules, concentration 7.4 mM with an additional peptide LYS.

Liquid-liquid Phase separation

The process by which two immiscible liquid phases separate.

Liquid-liquid phase separation is a phenomenon where two liquids that don't mix, like oil and water, form distinct layers. This happens in biological systems too, when molecules clump together to form compartments or droplets within cells.

Condensate

A concentrated solution or a state of matter where molecules cluster together.

A condensate is like a clump of molecules in a solution that are attracted to each other and stick together. This happens in cells when proteins or RNA molecules group together to form droplets, which can have specific functions.

Peptide

A short chain of amino acids linked together.

Peptides are like tiny chains made up of building blocks called amino acids. They're important in many biological processes, including signaling and regulating cell activity.

ADMA

Aspartic acid methyl ester analogue

ADMA is a chemical compound that mimics the behavior of another molecule called aspartic acid. It's used in research to study how cells function and interact.

ARG

Arginine

Arginine is an amino acid that plays a role in many biological processes. It's involved in muscle growth, wound healing, and immune function.

LYS

Lysine

Lysine is an essential amino acid that's important for growth and development. It plays a role in the production of enzymes and hormones.

RNA

Ribonucleic acid

RNA is a molecule that carries genetic information from DNA to ribosomes, where proteins are made. It's essential for all living organisms.