RESEARCH: COVID-19
FOLDING PROJECT #14825 PROFILE

Folding@home is using computer power to study proteins from the Coronavirus (SARS-CoV-2). These proteins could be targets for new drugs. You can help by running special projects on your computer. Find out more at https://foldingathome.org/news/

CORONAVIRUS PROJECT These projects are part of Folding@home’s efforts to assist researchers around the world taking up the global fight against COVID-19.

At the time of release, this is the latest news update: https://foldingathome.org/2020/03/10/covid19-update/ These projects are CPU projects to simulate COVID-19 proteins to learn about their dynamics and function.

These supplement high-priority GPU projects of the main protease as well as the COVID-19 receptor binding domains.

All can be considered potential drug targets. Please stay tuned to https://foldingathome.org/news/ for more current updates. ALL of these projects are Coronavirus SARS-CoV-2 main protease in complex with a potential inhibitor: series project number ------- ------- 72_RL 14800
387_RL 14801
387_RL 14802
387_RL 14803
387_RL 14804
387_RL 14805
387_RL 14806
387_RL 14807
387_RL 14808
AGG_RL 14809
AGG_RL 14810
AGG_RL 14811
AGG_RL 14812
AGG_RL 14813
AGG_RL 14814
AGG_RL 14815
AGG_RL 14816
BRO_RL 14717
BRO_RL 14718
BRO_RL 14719
BRO_RL 14820
MLTN_RL 14821
MS0323_RL 14822
MS0326_RL 14823
MS0326_RL 14824
MS0331_RL 14825
MS0406_RL 14852
MS0406-2_RL 14854
GUZ_RL 14858.

CORONAVIRUS

A type of virus that causes respiratory illness.

Coronavirus is a large family of viruses that can cause diseases in animals and humans. Some coronaviruses are mild, like the common cold, while others can be more serious, such as SARS-CoV-2, which causes COVID-19.

COVID-19

Coronavirus Disease 2019

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Symptoms can range from mild to severe and include fever, cough, shortness of breath, and loss of taste or smell.

SARS-CoV-2

Severe Acute Respiratory Syndrome Coronavirus 2

SARS-CoV-2 is the virus that causes COVID-19. It is a type of coronavirus that spreads primarily through respiratory droplets.

Main Protease

An enzyme essential for viral replication.

The main protease is a crucial enzyme that coronaviruses need to replicate. It helps cut proteins into smaller pieces needed for the virus to make more copies of itself.

Drug Targets

Molecules or proteins that can be inhibited by drugs.

Drug targets are specific molecules or proteins within a disease-causing organism (like a virus) that scientists try to block with drugs. Inhibiting these targets can help stop the disease from progressing.