RESEARCH: COVID-19
FOLDING PROJECT #14816 PROFILE

Folding@home is using your computer power to study proteins from the coronavirus. This helps scientists learn how these proteins work and find potential drugs to fight COVID-19. The project simulates protein interactions with possible inhibitors, aiming to identify effective treatments. Stay updated on their website for the latest news and developments.

CORONAVIRUS PROJECT These projects are part of Folding@home’s efforts to assist researchers around the world taking up the global fight against COVID-19.

At the time of release, this is the latest news update: https://foldingathome.org/2020/03/10/covid19-update/ These projects are CPU projects to simulate COVID-19 proteins to learn about their dynamics and function.

These supplement high-priority GPU projects of the main protease as well as the COVID-19 receptor binding domains.

All can be considered potential drug targets. Please stay tuned to https://foldingathome.org/news/ for more current updates. ALL of these projects are Coronavirus SARS-CoV-2 main protease in complex with a potential inhibitor: series project number ------- ------- 72_RL 14800
387_RL 14801
387_RL 14802
387_RL 14803
387_RL 14804
387_RL 14805
387_RL 14806
387_RL 14807
387_RL 14808
AGG_RL 14809
AGG_RL 14810
AGG_RL 14811
AGG_RL 14812
AGG_RL 14813
AGG_RL 14814
AGG_RL 14815
AGG_RL 14816
BRO_RL 14717
BRO_RL 14718
BRO_RL 14719
BRO_RL 14820
MLTN_RL 14821
MS0323_RL 14822
MS0326_RL 14823
MS0326_RL 14824
MS0331_RL 14825
MS0406_RL 14852
MS0406-2_RL 14854
GUZ_RL 14858.

CORONAVIRUS

A group of related viruses that cause respiratory illnesses.

Coronaviruses are a large family of viruses that can cause diseases in humans and animals. Some coronaviruses cause mild symptoms like the common cold, while others can lead to severe illness such as COVID-19.

COVID-19

Coronavirus disease 2019

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. It can cause a range of symptoms, from mild to severe, and can lead to complications like pneumonia.

SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2

SARS-CoV-2 is the virus that causes COVID-19. It is a type of coronavirus that is highly contagious and can spread easily from person to person.

Main Protease

An enzyme essential for viral replication.

The main protease is a crucial enzyme found in coronaviruses. It plays a vital role in the virus's ability to replicate and spread within the body. Inhibiting this enzyme is a key strategy for developing antiviral drugs.

Inhibitor

A substance that blocks or reduces the activity of another substance.

Inhibitors are molecules that can bind to enzymes or other biological targets and prevent them from functioning properly. They are widely used in drug development to target specific disease pathways.

Drug Targets

Molecules or pathways that are potential targets for drug action.

Drug targets are specific molecules or biological processes involved in disease development. By targeting these pathways with drugs, scientists aim to treat and manage diseases effectively.