RESEARCH: COVID-19
FOLDING PROJECT #14809 PROFILE

Researchers are using computer simulations to study proteins from the coronavirus (SARS-CoV-2). This project helps scientists understand how these proteins work and find potential drug targets. You can help by running simulations on your computer through Folding@home. For more details, visit https://foldingathome.org.

CORONAVIRUS PROJECT These projects are part of Folding@home’s efforts to assist researchers around the world taking up the global fight against COVID-19.

At the time of release, this is the latest news update: https://foldingathome.org/2020/03/10/covid19-update/ These projects are CPU projects to simulate COVID-19 proteins to learn about their dynamics and function.

These supplement high-priority GPU projects of the main protease as well as the COVID-19 receptor binding domains.

All can be considered potential drug targets. Please stay tuned to https://foldingathome.org/news/ for more current updates. ALL of these projects are Coronavirus SARS-CoV-2 main protease in complex with a potential inhibitor: series project number ------- ------- 72_RL 14800
387_RL 14801
387_RL 14802
387_RL 14803
387_RL 14804
387_RL 14805
387_RL 14806
387_RL 14807
387_RL 14808
AGG_RL 14809
AGG_RL 14810
AGG_RL 14811
AGG_RL 14812
AGG_RL 14813
AGG_RL 14814
AGG_RL 14815
AGG_RL 14816
BRO_RL 14717
BRO_RL 14718
BRO_RL 14719
BRO_RL 14820
MLTN_RL 14821
MS0323_RL 14822
MS0326_RL 14823
MS0326_RL 14824
MS0331_RL 14825
MS0406_RL 14852
MS0406-2_RL 14854
GUZ_RL 14858.

CORONAVIRUS

A type of virus that causes respiratory illness.

Coronaviruses are a large family of viruses that can cause illnesses ranging from the common cold to more severe diseases like SARS and MERS. COVID-19 is a new coronavirus disease that was first identified in 2019.

COVID-19

Coronavirus disease 2019

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. It can cause a range of symptoms, from mild to severe, and can lead to complications like pneumonia and respiratory failure.

SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2

SARS-CoV-2 is the virus that causes COVID-19. It is a type of coronavirus that was first identified in Wuhan, China, in 2019.

Main Protease

An enzyme essential for viral replication.

The main protease is a key enzyme produced by the SARS-CoV-2 virus. It plays a crucial role in replicating the virus by cleaving viral proteins into smaller, functional pieces.

Inhibitor

A substance that blocks or reduces the activity of an enzyme.

Inhibitors are molecules that can bind to enzymes and prevent them from carrying out their function. They are often used in medicine to treat diseases by blocking the activity of harmful enzymes.

Drug Targets

Molecules or biological pathways that are potential targets for drug development.

Drug targets are specific molecules or processes within the body that are thought to be involved in disease. Developing drugs that can modulate these targets is a central goal of pharmaceutical research.