RESEARCH: CANCER
FOLDING PROJECT #12003 PROFILE

This project relates to Class A GPCRs, which are important proteins that control many body functions. They act like messengers, sending signals within our cells. Understanding how they work can help create better drugs for diseases like cancer, diabetes, and mental health conditions.

Class A GPCRs: Class A GPCRs are pivotal drug targets in our body, as they are involved in regulating almost all homeostatic processes in the human body.

It is estimated that around 35% of all drugs currently approved by the FDA target one of these GPCRs.

These proteins act like 'molecular telephones' and transmit signals from outside the cell to inside the cell.

Here, we aim to study the process that underlies their action on our body.

This is integral for providing insights into the protein's function and design better and new drugs targeting cancer, diabetes, depression and anxiety.

GPCRs

G protein-coupled receptors

GPCRs are a large family of cell surface receptors that play crucial roles in transmitting signals from the outside to the inside of cells. They are involved in many physiological processes and are major targets for drug development.

FDA

Food and Drug Administration

The FDA is a US government agency responsible for ensuring the safety and effectiveness of drugs, medical devices, and other products.

Cancer

Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells.

Diabetes

Diabetes is a chronic condition that affects how the body regulates blood sugar levels.

Depression

Depression is a mood disorder characterized by persistent feelings of sadness, hopelessness, and loss of interest.

Anxiety

Anxiety is a feeling of worry, nervousness, or unease.