RESEARCH: CANCER
FOLDING PROJECT #14937 PROFILE

Class F Receptors help control how cells develop. When these receptors are overactive, they can contribute to cancers like Basal Cell Carcinoma and Medulloblastoma. This project uses computer simulations to understand how these receptors work, hoping to find new ways to treat these diseases.

Class F Receptors Class F Receptors are involved in the control of cell differentiation.

Over-activation of these proteins has links to Basal Cell Carcinoma and Medulloblastoma.

Through simulations we aim to understand the activation mechanisms of these proteins, giving us a way to probe into the pathogenesis of the disease.

Class F Receptors

A family of G protein-coupled receptors involved in cell signaling and differentiation.

Class F Receptors are a group of proteins found on the surface of cells. They act as receptors, receiving signals from other molecules and triggering responses within the cell. These receptors are important for processes like cell growth, development, and survival. Disruptions in their function can contribute to diseases like Basal Cell Carcinoma and Medulloblastoma.

Basal Cell Carcinoma

A type of skin cancer that originates in the basal cells.

Basal Cell Carcinoma is the most common type of skin cancer. It develops from the basal cells, which are found in the deepest layer of the epidermis (outer skin layer). This cancer often appears as a pearly or waxy bump and can be slow-growing.

Medulloblastoma

A type of malignant brain tumor that arises from the cerebellum.

Medulloblastoma is a serious type of cancer that begins in the cerebellum, a part of the brain responsible for balance and coordination. It's most common in children.