RESEARCH: CANCER
FOLDING PROJECT #14935 PROFILE

This project looks at Class F Receptors, which control how cells develop. Overactive receptors can cause cancer like Basal Cell Carcinoma and Medulloblastoma. By using computer models, researchers want to figure out how these receptors work, helping us understand and treat these diseases better.

Class F Receptors Class F Receptors are involved in the control of cell differentiation.

Over-activation of these proteins have links to Basal Cell Carcinoma and Medulloblastoma.

Through Simulations we aim to understand the activation mechanisms of these proteins, giving us a way to probe into the pathogenesis of the disease.

Class F Receptors

Receptors that play a role in cell differentiation.

Class F receptors are a type of protein found on the surface of cells. They receive signals from other molecules and help to control how cells grow and develop. Overactivation of these receptors has been linked to certain types of cancer, such as basal cell carcinoma and medulloblastoma.

Basal Cell Carcinoma

A common type of skin cancer that originates in the basal cells.

Basal cell carcinoma is the most common form of skin cancer. It develops from the basal cells, which are located in the deepest layer of the epidermis (outermost layer of skin). Basal cell carcinomas typically appear as pearly or waxy bumps and can grow slowly.

Medulloblastoma

A type of malignant brain tumor that arises in the cerebellum.

Medulloblastoma is a fast-growing brain tumor that occurs most often in children. It originates in the cerebellum, a part of the brain responsible for balance and coordination. Medulloblastoma can spread to other parts of the body.