RESEARCH: CANCER
FOLDING PROJECT #14936 PROFILE

This project studies Class F Receptors which help control cell development. Too much activity in these receptors can lead to cancers like Basal Cell Carcinoma and Medulloblastoma. By creating computer models, researchers hope to understand how these receptors work and find new ways to treat these diseases.

Class F Receptors Class F Receptors are involved in the control of cell differentiation.

Over-activation of these proteins has links to Basal Cell Carcinoma and Medulloblastoma.

Through simulations we aim to understand the activation mechanisms of these proteins, giving us a way to probe into the pathogenesis of the disease.

Class F Receptors

Receptors that play a role in cell differentiation and signaling.

Class F receptors are a type of protein found on the surface of cells. They receive signals from other cells and molecules, which helps to control how cells grow and develop. Over-activation of these receptors can lead to certain types of cancer, such as basal cell carcinoma and medulloblastoma.

Basal Cell Carcinoma

A type of skin cancer that originates in the basal cells.

Basal cell carcinoma is the most common type of skin cancer. It develops in the basal cells, which are located in the deepest layer of the epidermis (outermost layer of skin). Early detection and treatment are important to prevent it from spreading.

Medulloblastoma

A type of malignant brain tumor that arises in the cerebellum.

Medulloblastoma is a highly aggressive type of childhood brain cancer that originates in the cerebellum, a part of the brain responsible for balance and coordination. Treatment usually involves surgery, chemotherapy, and radiation therapy.