RESEARCH: CANCER
FOLDING PROJECT #17622 PROFILE
PROJECT TEAM
Manager(s): Sukrit SinghInstitution: Memorial Sloan-Kettering Cancer-Center
Project URL: View Project Website
WORK UNIT INFO
Atoms: 329,840Core: 0x22
Status: Public
Related Projects
TLDR; PROJECT SUMMARY AI BETA
Scientists are using powerful computer simulations to study how changes in proteins can affect their function. They're focusing on a complex protein called RIPK2, which is involved in immune responses. By making tiny changes to the protein and observing the results, they hope to gain a better understanding of diseases and develop new treatments.
Note: This TLDR is a simplication and may not be 100% accurate.OFFICAL PROJECT DESCRIPTION
The previous FEC work unit test was completed successfully so now we're running larger "full size" WUs that are more scientifically useful for studying protein mutations with Free Energy Calculations.
As before, the approach and technology are similar to the Moonshot, but these set of projects instead are studying protein mutations and are much larger (since proteins are also much larger) In this case we are trying out multiple mutations and their impact upon a protein-protein of a dimerization complex (RIPK2), the most complex case.
RELATED TERMS GLOSSARY AI BETA
FEC
Free Energy Calculations
A computational method used to predict the stability of protein structures and interactions.
WUs
Work Units
Individual tasks or computations within a larger research project.
Moonshot
A large-scale, ambitious research project.
A program with the goal of making significant scientific breakthroughs.
Protein Mutations
Changes in the DNA sequence of a protein-coding gene.
Alterations in the genetic code that can affect the structure and function of proteins.
Free Energy Calculations
A computational method used to predict the stability of protein structures and interactions.
Calculations that estimate the energy changes associated with chemical reactions or conformational changes in molecules.
Dimerization Complex
A complex formed by two protein molecules interacting with each other.
A structure composed of two identical or similar protein subunits that bind together to perform a specific function.
RIPK2
Receptor-Interacting Protein Kinase 2
A protein involved in cell signaling pathways that regulate inflammation and immune responses.
PROJECT FOLDING PPD AVERAGES BY GPU
Data as of Sunday, 26 April 2026 00:37:58|
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
|---|---|---|---|---|---|---|---|
| 1 | GeForce RTX 3090 GA102 [GeForce RTX 3090] |
Nvidia | GA102 | 7,408,345 | 1,901,972 | 3.90 | 6 hrs 10 mins |
| 2 | GeForce RTX 3070 Lite Hash Rate GA104 [GeForce RTX 3070 Lite Hash Rate] |
Nvidia | GA104 | 3,517,530 | 1,484,236 | 2.37 | 10 hrs 8 mins |
| 3 | GeForce RTX 2080 Ti Rev. A TU102 [GeForce RTX 2080 Ti Rev. A] M 13448 |
Nvidia | TU102 | 3,017,087 | 1,570,741 | 1.92 | 12 hrs 30 mins |
| 4 | GeForce GTX 1080 Ti GP102 [GeForce GTX 1080 Ti] 11380 |
Nvidia | GP102 | 1,755,507 | 1,299,604 | 1.35 | 17 hrs 46 mins |
| 5 | GeForce GTX 980 GM204 [GeForce GTX 980] 4612 |
Nvidia | GM204 | 832,076 | 919,692 | 0.90 | 26 hrs 32 mins |
PROJECT FOLDING PPD AVERAGES BY CPU BETA
Data as of Sunday, 26 April 2026 00:37:58|
Rank Project |
CPU Model |
Logical Processors (LP) |
PPD-PLP AVG PPD per 1 LP |
ALL LP-PPD (Estimated) |
Make |
|---|