RESEARCH: CANNABINOID
FOLDING PROJECT #12707 PROFILE

This project relates to cannabinoid receptors, which control things like pain, appetite, and learning. By testing different drugs on these receptors, we can learn how they work and if a drug is safe and effective for treating conditions.

Cannabinoid G Protein Coupled Receptors Improper signaling through Cannabinoid receptors is linked to drug addiction, pain perception, appetite regulation and learning.

Simulation of these proteins with different small molecules helps us to understand their function and the selectivity/efficacy of these potential drugs to the nervous system.

Cannabinoid

A class of psychoactive compounds found in cannabis plants.

Cannabinoids are a group of chemicals derived from the cannabis plant. They interact with the body's endocannabinoid system, which plays a role in regulating various functions like mood, appetite, sleep, and pain perception. Different cannabinoids have varying effects, some producing psychoactive experiences (like THC) while others may offer therapeutic benefits (like CBD).

G Protein Coupled Receptors

Receptors that activate G proteins upon ligand binding.

G protein-coupled receptors (GPCRs) are a large family of cell surface receptors involved in transmitting signals within cells. When a molecule called a ligand binds to a GPCR, it triggers a cascade of events inside the cell by activating a protein called a G protein. This activation leads to various cellular responses, including changes in gene expression, metabolism, and behavior.