RESEARCH: CANCER
FOLDING PROJECT #18002 PROFILE

PROJECT TEAM

Manager(s): Samuel Lotz
Institution: Roivant Sciences (prev. Silicon Therapeutics)
Project URL: View Project Website

WORK UNIT INFO

Atoms: 63,451
Core: OPENMM_22
Status: Public

Related Projects

TLDR; PROJECT SUMMARY AI BETA

This project relates to using computer simulations to create new medicines that can destroy harmful proteins in the body. These medicines could be used to treat cancer and other diseases.

Note: This TLDR is a simplication and may not be 100% accurate.

OFFICAL PROJECT DESCRIPTION

These simulations are helping to develop new Targeted Protein Degradation (TPD) therapies for treating cancer and many other diseases.

RELATED TERMS GLOSSARY AI BETA

Note: Glossary items are a high level summary and may not be 100% accurate.

Targeted Protein Degradation

TPD

Scientific: Biotechnology
Pharmacology / Drug Discovery

Targeted Protein Degradation (TPD) is a novel approach to treating diseases by promoting the breakdown of specific proteins involved in disease progression. This method utilizes small molecules that bind to target proteins and guide them towards degradation machinery within the cell, effectively reducing their harmful effects.


Therapies

Medical treatments intended to relieve or cure diseases

Scientific: Healthcare
Medicine / Treatment

Therapies are medical interventions designed to treat or manage diseases and improve patient well-being. These can include various approaches such as medication, surgery, radiation therapy, or lifestyle modifications.


Cancer

A disease characterized by uncontrolled cell growth and spread.

Pathological: Healthcare
Medicine / Oncology

Cancer is a group of diseases involving abnormal cell growth with the potential to invade surrounding tissues and spread to other parts of the body. It arises from genetic mutations that disrupt normal cellular processes.


Diseases

Conditions that impair normal bodily function.

Medical: Healthcare
Medicine / Pathology

Diseases are a broad range of conditions that affect the structure or function of the human body. They can be caused by various factors such as genetic predisposition, infections, lifestyle choices, or environmental exposures.

PROJECT FOLDING PPD AVERAGES BY GPU

Data as of Sunday, 26 April 2026 00:33:20
Rank
Project
Model Name
Folding@Home Identifier
Make
Brand
GPU
Model
PPD
Average
Points WU
Average
WUs Day
Average
WU Time
Average
1 GeForce RTX 2080 Ti Rev. A
TU102 [GeForce RTX 2080 Ti Rev. A] M 13448
Nvidia TU102 3,691,567 296,221 12.46 1 hrs 56 mins
2 TITAN Xp
GP102 [TITAN Xp] 12150
Nvidia GP102 2,525,579 260,740 9.69 2 hrs 29 mins
3 GeForce RTX 2070 Rev. A
TU106 [GeForce RTX 2070 Rev. A] M 7465
Nvidia TU106 1,669,655 226,882 7.36 3 hrs 16 mins
4 GeForce RTX 2060 Super
TU106 [GeForce RTX 2060 SUPER]
Nvidia TU106 1,450,153 216,687 6.69 3 hrs 35 mins
5 GeForce RTX 2060
TU104 [GeForce RTX 2060]
Nvidia TU104 1,358,820 211,890 6.41 3 hrs 45 mins
6 GeForce GTX 1070 Ti
GP104 [GeForce GTX 1070 Ti] 8186
Nvidia GP104 1,357,720 211,730 6.41 3 hrs 45 mins
7 GeForce RTX 2070
TU106 [GeForce RTX 2070] M 6497
Nvidia TU106 1,264,831 202,853 6.24 3 hrs 51 mins
8 GeForce RTX 2060
TU106 [Geforce RTX 2060]
Nvidia TU106 1,167,192 201,431 5.79 4 hrs 9 mins
9 GeForce RTX 2080 SUPER Mobile / Max-Q
TU104M [GeForce RTX 2080 SUPER Mobile / Max-Q]
Nvidia TU104M 1,155,636 201,297 5.74 4 hrs 11 mins
10 GeForce RTX 3060 Mobile / Max-Q
GA106M [GeForce RTX 3060 Mobile / Max-Q]
Nvidia GA106M 1,127,983 199,240 5.66 4 hrs 14 mins
11 GeForce GTX 980 Ti
GM200 [GeForce GTX 980 Ti] 5632
Nvidia GM200 1,078,072 196,314 5.49 4 hrs 22 mins
12 Tesla M40
GM200GL [Tesla M40] 6844
Nvidia GM200GL 958,108 188,519 5.08 4 hrs 43 mins
13 GeForce GTX 1070
GP104 [GeForce GTX 1070] 6463
Nvidia GP104 955,879 187,562 5.10 4 hrs 43 mins
14 GeForce GTX 1660 SUPER
TU116 [GeForce GTX 1660 SUPER]
Nvidia TU116 874,255 181,891 4.81 4 hrs 60 mins
15 GeForce RTX 2060 Mobile
TU106M [GeForce RTX 2060 Mobile]
Nvidia TU106M 838,080 154,823 5.41 4 hrs 26 mins
16 GeForce GTX 1660 Ti
TU116 [GeForce GTX 1660 Ti]
Nvidia TU116 808,497 176,355 4.58 5 hrs 14 mins
17 GeForce GTX 1660
TU116 [GeForce GTX 1660]
Nvidia TU116 786,782 176,596 4.46 5 hrs 23 mins
18 P104-100
GP104 [P104-100]
Nvidia GP104 645,556 165,257 3.91 6 hrs 9 mins
19 GeForce GTX 1060 6GB
GP106 [GeForce GTX 1060 6GB] 4372
Nvidia GP106 598,574 159,491 3.75 6 hrs 24 mins
20 GeForce GTX 1650 SUPER
TU116 [GeForce GTX 1650 SUPER]
Nvidia TU116 549,121 156,521 3.51 6 hrs 50 mins
21 GeForce GTX 1060 3GB
GP106 [GeForce GTX 1060 3GB] 3935
Nvidia GP106 541,686 155,903 3.47 6 hrs 54 mins
22 GeForce GTX 970
GM204 [GeForce GTX 970] 3494
Nvidia GM204 506,939 148,701 3.41 7 hrs 2 mins
23 P106-100
GP106 [P106-100]
Nvidia GP106 436,591 145,121 3.01 7 hrs 59 mins
24 GeForce GTX 1650 Ti Mobile
TU117M [GeForce GTX 1650 Ti Mobile]
Nvidia TU117M 399,870 140,232 2.85 8 hrs 25 mins
25 GeForce GTX 1650 Ti Mobile
TU116M [GeForce GTX 1650 Ti Mobile]
Nvidia TU116M 367,886 137,130 2.68 8 hrs 57 mins
26 GeForce GTX 1650
TU116 [GeForce GTX 1650] 2984
Nvidia TU116 366,059 136,128 2.69 8 hrs 55 mins
27 GeForce GTX 1650 Mobile / Max-Q
TU117M [GeForce GTX 1650 Mobile / Max-Q]
Nvidia TU117M 319,576 129,207 2.47 9 hrs 42 mins
28 GeForce GTX 960
GM206 [GeForce GTX 960] 2308
Nvidia GM206 288,530 126,131 2.29 10 hrs 29 mins
29 Quadro M4000
GM204GL [Quadro M4000]
Nvidia GM204GL 283,763 125,511 2.26 10 hrs 37 mins
30 GeForce GTX 1050 Mobile
GP107M [GeForce GTX 1050 Mobile]
Nvidia GP107M 243,359 119,364 2.04 11 hrs 46 mins
31 GeForce GTX 1050 Ti Mobile
GP107M [GeForce GTX 1050 Ti Mobile]
Nvidia GP107M 199,932 111,960 1.79 13 hrs 26 mins
32 GeForce GTX 690
GK104 [GeForce GTX 690] 3130
Nvidia GK104 173,593 106,988 1.62 14 hrs 47 mins
33 Radeon R9 200/300 Series
Hawaii [Radeon R9 200/300 Series]
AMD Hawaii 163,009 98,118 1.66 14 hrs 27 mins
34 GeForce GTX 660 Ti
GK104 [GeForce GTX 660 Ti] 2634
Nvidia GK104 160,303 104,086 1.54 15 hrs 35 mins
35 Quadro P1000
GP107GL [Quadro P1000]
Nvidia GP107GL 110,159 91,770 1.20 19 hrs 60 mins
36 Quadro K2200
GM107GL [Quadro K2200]
Nvidia GM107GL 99,846 88,917 1.12 21 hrs 22 mins
37 GeForce GTX 960M
GM107 [GeForce GTX 960M] 1439
Nvidia GM107 97,845 88,318 1.11 21 hrs 40 mins
38 GeForce GT 1030
GP108 [GeForce GT 1030] 1127
Nvidia GP108 96,894 87,246 1.11 21 hrs 37 mins
39 GeForce GTX 750 Ti
GM107 [GeForce GTX 750 Ti] 1389
Nvidia GM107 92,507 86,157 1.07 22 hrs 21 mins
40 GeForce GTX 660
GK106 [GeForce GTX 660]
Nvidia GK106 90,712 86,097 1.05 22 hrs 47 mins
41 GeForce GTX 750
GM107 [GeForce GTX 750] 1111
Nvidia GM107 88,669 85,651 1.04 23 hrs 11 mins
42 GTX 650 Ti Boost
GK106 [GTX 650 Ti Boost]
Nvidia GK106 84,138 83,832 1.00 23 hrs 55 mins
43 Quadro K1200
GM107GL [Quadro K1200]
Nvidia GM107GL 66,646 77,421 0.86 27 hrs 53 mins
44 Quadro K620
GM107GL [Quadro K620]
Nvidia GM107GL 46,072 68,645 0.67 35 hrs 46 mins

PROJECT FOLDING PPD AVERAGES BY CPU BETA

Data as of Sunday, 26 April 2026 00:33:20
Rank
Project
CPU Model Logical
Processors (LP)
PPD-PLP
AVG PPD per 1 LP
ALL LP-PPD
(Estimated)
Make