RESEARCH: CANCER
FOLDING PROJECT #17800 PROFILE

This project explores BCL-XL, a protein that stops cell death, as a target for lymphoma treatment. It's testing new methods to find the best drugs, including 'adaptive sampling', which helps researchers make smarter choices about which drugs to test.

BCL-XL apoptotic protein --- a drug target in lymphoma.

More info coming soon.

Together with project 17801 this is also testing new methodology --- adaptive sampling.

This is the standard sampling version of the system.

BCL-XL

B-cell lymphoma-extra large

BCL-XL is a protein that plays a role in cell survival. It is often overexpressed in lymphoma cells, making it a potential drug target.

apoptotic protein

A protein involved in programmed cell death (apoptosis).

Apoptotic proteins are essential for regulating cell death. They play a crucial role in removing damaged or unwanted cells, maintaining tissue homeostasis, and preventing the development of diseases like cancer.

drug target

A molecule or biological pathway that is a focus for developing new medications.

Drug targets are specific molecules or processes within the body that are involved in disease pathways. By inhibiting or modulating these targets, drugs can treat or prevent diseases.

lymphoma

A type of cancer that affects the lymphatic system.

Lymphoma is a group of cancers that originate in the lymphocytes, a type of white blood cell. It can affect different parts of the lymphatic system, such as lymph nodes, spleen, and bone marrow.