The proteasome subunit hRpn13 is a critical component of cell maintenance and reproduction, serving to help recruit ubiquitinated targets for protein degradation.
Inhibitors of hRpn13 are a promising avenue for anti-cancer therapeutics. This project aims to simulate the Pru domain of hRpn13 which contains many different surfaces at which interactions with proteins and peptides occur, and undergoes significant conformational change upon binding.
Compare community-sampled Folding@Home output for the GPUs and CPUs processing this project.
|
Rank Project |
Model Name Folding@Home Identifier |
Make Brand |
GPU Model |
PPD Average |
Points WU Average |
WUs Day Average |
WU Time Average |
|---|---|---|---|---|---|---|---|
| 1 | Instinct MI325X Aqua Vanjaram [Instinct MI325X] |
AMD | Aqua Vanjaram | 11,533,122 | 18,242 | 632.23 | 0 hrs 2 mins |
| 2 | Radeon RX 7900XT/XTX/GRE Navi 31 [Radeon RX 7900XT/XTX/GRE] |
AMD | Navi 31 | 10,413,912 | 18,242 | 570.88 | 0 hrs 3 mins |
| 3 | Radeon RX 9070(XT) Navi 48 [Radeon RX 9070(XT)] |
AMD | Navi 48 | 6,079,914 | 18,242 | 333.29 | 0 hrs 4 mins |
| 4 | Intel Arc Pro B70 Battlemage G31 [Intel Arc Pro B70] |
Intel | Battlemage G31 | 4,297,159 | 18,242 | 235.56 | 0 hrs 6 mins |
| 5 | Instinct MI300A Aqua Vanjaram [Instinct MI300A] |
AMD | Aqua Vanjaram | 360,401 | 18,242 | 19.76 | 1 hrs 13 mins |